Research

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Asim Abdel-Mageed, PhD
Active Research Projects

Dr. Abdel-Mageed’s laboratory primarily conducts basic research into the cellular and molecular mechanisms underlying urologic diseases, with a particular focus on prostate and bladder cancer. His laboratory emphasizes identifying molecular determinants of prostate cancer progression through both in vitro and in vivo experimental models.

Key research areas include:

  • Targeting tumor-derived exRNA-containing microvesicles by high-throughput screening

  • The estrogen-ER axis in prostate cancer disparities

  • Adipose stem cell–based therapeutic targeting of residual androgens in African American patients with bone metastatic prostate cancer

 

Sikka

Suresh Sikka, PhD

Dr. Sikka’s research encompasses male infertility, sexual dysfunction, genitourinary inflammation, prostate diseases, environmental reproductive toxicology, oxidative stress and antioxidants, sperm safety, forensic applications, endocrine disruptors, and andropause.

Key research areas include:

  • Male Infertility: diagnosis, treatment, assisted reproduction technology, oxidative stress, testicular toxicology, standardized semen evaluation training, DNA identification, and chromosome evaluation.
  • Sexual Health: erectile dysfunction, Peyronie’s disease, oxidative stress, and stem cell research.
  • Prostate Health: benign prostatic hyperplasia,  prostatitis and genitourinary inflammation, lower urinary tract symptoms, male aging (andropause), hypogonadism and hormone replacement, and prostate cancer.

 

Manesh Kumar PannerSelvam, PhD

Dr. Panner-Selvam’s research focuses on reproductive biology, with particular expertise in sperm and seminal plasma proteomics. His laboratory applies advanced bioinformatics tools to investigate sperm protein function in male infertility and to identify novel biomarkers with diagnostic and prognostic potential.

Active Research Projects

  • Understanding the role of seminal exosome proteins in sperm dysfunction

  • Investigating sperm telomere length as a novel diagnostic marker of DNA damage

  • Assessing the impact of COVID-19 on male reproductive health

Wayne Hellstrom, MD, FACS

Dr. Wayne Hellstrom has been a mentor and a researcher for over 34 years at Tulane. His work significantly attracts medical students as well as residents who present research findings at meetings, such as the American Society of Andrology (ASA), the Sexual Medicine Society of North America (SMSNA), and the American Urological Association (AUA), and who subsequently publish manuscripts regarding such research in highly respected journals.

Active Research Projects

  • Patient-derived tunical albuginea Xenograft model: a new animal model of Peyronie’s disease
  • Molecular mechanisms of penile traction for penile rehabilitation in a bilateral cavernous nerve crush injury rat model